The tow imposed on the limb above inflammation home to slow venous blood flow, better absorption of antibiotics in the tissues of the limbs. Vnutricostnoe introduction of antibiotics allows for the creation of the necessary concentration in the tissues and blood. Method worth intent. The grand localization processes at the extremities for a high concentration of antibiotics in the middle of inflammation 06'52 its usefulness vnutriarterialnoe introduction of the preparation. Variety внутриартериального of antibiotics are long внутриартериальная cefuroxim and регионарная перфузия. A positive feature vnutriarterialnogo introduction of antibiotics in the treatment of diseases grand hand is the possibility of creating a high concentration of antibiotics in a limited stretch limbs, and the use of mangetki sfigmomanometra to hold drug in the tissues of the required time. Moreover, the introduction of vnutriarterialnoe antibiotics with a novohammo sufficient chemicals, which allows a smooth operation. Autopsy fester, flegmona, grand damp revealed in the lack of draining wounds. The willingness to have a high concentration of antimicrobial drugs in the middle of inflammation led to the use of vnutriarterialnogo ways of medicinal substances. In this way the concentration of drugs in organs and tissues abdominal increased several times over vnutrimyshecnam and intravenous routes introduction. The agent gnano-vospalitiona disease is now Staphylococcus, which is highly resistant to antibiotics the "first generation" - penitsillino, streptomitino, tetratziklino. Therefore, the use of antibiotics on the basis of sensitivity to the microflora is a prerequisite for rational antimicrobial therapy. Inefficiency widespread antibiotics determines whether the use of new drugs, the protivostafilokokkov th activity. These new antibiotics, drugs reserve include automotive aminoglikozida, zefalosporin, linkomicin, fuzidin etc. Besides, were widely used drugs nitrofuranove (furagin, furazolidin etc.). The staphylococcus infection soft tissue effective metitillin, oxacillin, penicillin preparations, ristomicin; In a mixed infection most effective aminoglikozida, combination with antibiotics sulfanilamidami prolonged action and nitrofuranami. Erythromycin high antibacterial activity against resistant penitsillino, tetratziklino, streptomitino and other antibiotic strains of staphylococcus. Effect of erythromycin increased when combined with tetracycline, oleandomitinom. In clinical practice to develop eritromitino rapid sustainability microflora, and the testimony to be applied in patients with gnanami diseases to be serious cases of resistant to other agents germline. Among the antibiotics are differences in the effects on microbial cell to be determined not only to the species specificity of influenza, but also внутривидовыми biological characteristics. Thus, aminoglikozida, polimiksin operate on reproducing microbes, and the same kinds of causes outside reproduction they did not act. Therefore, the use of antibiotics in chronic infection weak.