limited capacity

The prognosticeski adverse viral complications in the form of interstitial pnevmonita, with 80-90% fatality raises the Cmv-infection. Among other possible causes of infectious complications, it should be noted inkapsulirovanne mikroorgaouizma and protozoa (pnevmotsysta). Along with haemorrhagic and infectious complications after TCM development may veno-occluzionna disease (WOB), the frequency of which is about 5% after ATKM to 10-15% for Altkm. The WOB has been in patients with previous violations of the liver, as well as the application of certain drugs in the treatment conditioning therapy. Major manifestations VOB are growing gepatomegalia, jelthe and astitu. Spironolactona, glukokortikoida and saluretiki so little case of VOB to 50%. After prizivlenia bone marrow and restore blood kostnomozgovy patients who completed ATKM, can be discharged from hospital under observation dynamic gematologa. After Altkm at this time that any heavy complications, the most dangerous of which is RTPH. Acute RTPH usually develops within the first 100 days after Altkm, with the defeat of the skin, gastrointestinal tract and liver. The symptoms of acute RTPH varies : clinical manifestations vary its modestly expressed makulopapulezna disease, subclinical raise cium frequent and liquid stool to generalized eritrodermii education and bull deskwamaziei cancer, rezcaichei jaundice, profuznogo diarrhoea and intestinal obstruction. Prevention and treatment RTPH conducted by immunosupressorov (cyclosporine A, methotrexate, PREDNISOLONE), but the rate remains high (30-50%). Chronic RTPH more frequently in patients after acute RTPH, but can develop and prevailed. In RTPH chronic infection the same as that used in RTPH acute, as well as the lungs, kostno-myshecnaya system mucous membranes of the mouth, eyes. The symptoms range from mild conjunctivitis and subklinicakih functional liver to fatal complications. The most effective for the treatment of chronic RTPH as in acute RTPH are glukokortikoida, ciclosporin A and methotrexate. Despite the many difficult complications TCM CCTS and the methods of choice in many diseases of the blood, since it gave better results than conventional treatment. Thus, in case of resistance to routine treatments heavy thoughts anaemia, accompanied by almost 100% fatality after Altkm bezretidius year survival rate is 60-80%. Comparison of chemotherapy and TCM (bezretidius five-year survival rate as a percentage of the group of bone-marrow transplants). (see image) According to the International Registry bone-marrow transplants likelihood old bezretidivna survival after Altkm is on average three times higher than that of patients with incorporating standard polychemotherapy. The T depends to a large extent on timeliness of the act. The Altkm the MoU in the chronic phase of the probability old bezretidivna survival on average five times higher than that of patients in blastnom krize. TCM is seen as an effective method of treatment for liver ionizing radiation. At the same time, however, it is necessary to take into account a number of characteristics associated with radiation injury bone marrow. Experience help participants cope with the aftermath of the accident at the Chernobyl nuclear power plant has limited capacity Altkm in acute radiation sickness. In this context, a much more promising autologicnogo harvesting bone marrow from groups with high-risk ray damage to their ATKM if necessary. Thus, TCM empowers treatment of gemoblastozah, tumorous haemogenic desplaziah and solid tumors. Risk TCM can be reduced by proper selection of patients and strict contraindications. Future prospects and improved results relate TCM : * the increase in the number ATKM cleaned bone marrow; * Increase in the number of Altkm gistosovmestimah rock donors; * Extension of the scope of the CCTS; * The use of growth factors (granulocyte, granulomonocitarnyi koloniestimulirute factors interleikin 3 and 6) in order to reduce the length of zitopenia and rates of infectious complications after TCM; * from the use of biological products (alfa-interferon, interleykin-2) to reduce the frequency of relapse after TCM.