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PostSubject: haemorrhagic syndrome   Fri Apr 06, 2007 2:55 pm

Our body contains factors that control, and more affecting education trombov. The blood contains factors such as antitromboplastin, antitrombin and heparin, which can monitor down at various stages. So if the tissue is a small number tromboplastina then it could be enough to start the process of downsizing and activate X factor. However, in this case, coagulation can be prevented by heparin. Heparin - polysaccharide produced in the fat cells. His act is a violation of the process of transforming protrombina in trombin. Antitrombin, is a complex matter, which prevents moving fibrinoguena in fibrin. Antitromboplastin (activated S-belok) inhibits activation V and VIII of blood clotting. Slowing down the process may occur : 1) a decrease in vitamin C in food that reduces protrombina; 2) to reduce the number of platelets, which reduces aguiruth down factors; 3), in liver disease leading to a decrease in protein involved in the liquidation and factors activate out; 4), with the diseases of genetic nature, where in the body do some coagulation factors (eg VIII - antigemofiliceski); 5), raising fibrinolizina content in the blood. The hypercoagulable may occur : 1) the suppression of the local activity and антитромбина тромбопластина (С-активированного protein) in the small vessels, most often it is small venous blood and leads to the formation of тромбов; 2) at high surgical interventions causing extensive damage to tissue; 3) with the express EMG receptacles by increasing charges in the vascular wall (endotelia) and the accumulation of ions Ca2 + on it. Individual episodes of increased bleeding can be separated by many months and even years, and then arise frequently. Therefore, for the diagnosis of hereditary defects hemostasis, it is extremely important to carefully documented history not only to the patient, but all his relatives. Moreover, we must know and the type of bleeding from the patient and relatives taking a closer look at the minimum traits bleeding-cyclical : skin haemorrhagic syndrome, or bleeding after injuries, cuts, the duration of menstrual bleeding in female gemartrozy etc. In clinical practice to provide several types of bleeding : 1. Gematomny type-a painful extensive bleeding in the subcutaneous fat, under aponeurozy in serosnye envelope in the muscles and joints usually after injuries to the development of trade back, contractures, pathological fractures. There are long, profuzne traumatic and postoperative bleeding, less-spontaneous. Later pronounced character bleeding, a few hours after the injury. Gematomny type characteristic of hemophilia A and B (deficit factor VIII and IX). 2. Petehialno-piatnysta (синячковый), or микроциркуляторный type характеризуемся петехиями, экхимозами on the skin and mucous membranes shells spontaneous (arising mainly at night length haemorrhage in the skin and mucous membranes), or arising out of the slightest bleeding injuries. Bruises are rarely kinetic not suffering. ORIONE bleeding has not (except tonzillacktomii). Frequent and dangerous bleeding in the brain;

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